“We have opened a small door to enormous opportunities to discover new diseases and explanations for known diseases. And we’re already working on that.”

- Maxim Itkin, MD, director, CHOP/HUP Center for Lymphatic Imaging and Interventions Program

Going with the Flow: How Lymphatics is Emerging as Medicine’s Newest Specialty

At first blush, the newest emerging field in medicine might sound very old: Lymphatics. Medicine has put so little emphasis on lymph, a protein-filled fluid that flows through vessels throughout most of the body, that the term can sound as archaic as doctors treating the …

Pediatricians May Better Help Parents Quit Smoking With Decision Support Tool

A parent’s love for a child is a powerful motivator. But when it comes to quitting smoking, often even the strongest motivation, in itself, is not enough. Only about 5 percent of smokers successfully quit each year, although many more try. That is why researchers …

Discovering How a Neurological ‘Pit Crew’ Keeps the Brain on Track

Imagine taking neuroscientists to a NASCAR race. While most spectators keep their eyes on the speeding cars, you might catch a few scientists in the crowd instead watching the activities of the pit crews at work on the sidelines, helping drivers to refuel and repair …

Scientists Identify Molecule Controlling Inflammatory Immune Response

When bacteria or viruses invade, the body’s ability to rapidly deploy white blood cells to attack the invader is a remarkable biological feat. But these rapid-attack cells, called myeloid cells, ideally work only as first responders to keep a pathogen contained. When responding to an …

Study Confirms Increasing Endocrine Disorders in Aging Childhood Cancer Survivors

A notable glowing success in the world of pediatric oncology is that there are more candles lighting up birthday cakes of young cancer survivors. As the years add up, these milestones are also significant reminders that cancer survivors must remain vigilant throughout their lifetimes to …

Neuroblastoma Drug Candidates Target Key Henchmen of a Supervillain Oncogene

The oncogene MYC is a supervillain of the cancer world. This gene is known to power the activities of cancer cells in many types of tumors in children and adults. Its variant MYCN, which is active in the childhood cancer neuroblastoma, is associated with the …

Fresh Hope for Treating a Rare Progressive, Lysosomal Storage Childhood Disease

It took nearly a decade and the loss of two infants before Khalid and Jabin Shaikh finally learned what was going wrong. Their third child, Zain, a son, was born in 2007 and immediately whisked away to a pediatric hospital for testing in an effort …

New Neuroblastoma Research Scholars Program Supports Young Scientist

Young scientists may have passion and brilliant ideas, but unfortunately, they often do not add up to federal funding dollars. This is particularly problematic in pediatric cancer research, which receives just 4 percent of the National Cancer Institute’s $4.95 billion budget. Enter the Evan’s Victory …