August 2014

“When working with children and families, it’s important to really think through and identify any precautions that you can take in your research to protect them.”- Lisa A. Schwartz, PhD

Exploring Girls’ Responses to Breast Cancer Risk


Ours is the first generation where women are routinely tested for genetic mutations that may increase their risk for breast cancer. They are also increasingly aware of the implications of their cancer history and genetic testing results on their daughters. Researchers at The Children’s Hospital …

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Project to Investigate Opiate Dependence in Neonates


Every year, approximately 350,000 to 400,000 infants are treated in a neonatal intensive care unit (NICU), according to a report put out by the Health Resources and Service Administration. Of those, between 50 and 80 percent become dependent on the opiates — such as the …

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CHOP Investigators Study Safety of Rotavirus Vaccine in NICU


Clinicians in neonatal intensive care units (NICU) across the country are uncertain about when to administer rotavirus vaccination to infants whose medical conditions require prolonged hospital stays, so experts at The Children’s Hospital of Philadelphia conducted a study published in Pediatrics to explore safety concerns …

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Grant Will Support Hemophilia Therapy Investigation


The Children’s Hospital of Philadelphia’s Lacramioara Ivanciu, PhD, was one of five investigators who recently received funding through the Bayer Hemophilia Awards Program (BHAP). A “unique initiative dedicated to supporting innovative research and educational initiatives that benefit people with hemophilia,” the BHAP is administered by …

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Forced Looping a Viable Strategy to Reverse Globin Switch


Investigators at The Children’s Hospital of Philadelphia are exploring a new gene therapy approach that aims to reactivate the production of fetal hemoglobin as a potential intervention for patients with sickle cell disease. In the U.S., it is estimated that sickle cell disease affects 100,000 …

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Study Compares Lung Opening Strategies for Preterm Babies


When an infant is born, we usually think of the strenuous effort labor entails for the mother, but it also requires a fair amount of work on the baby’s part. A newborn quickly has to adapt to breathing air, which calls for a large set …

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Researchers Study Orexins’ Role in Resilience to Stress


Chronic stress, whether it is from illness, interpersonal relationships, or other social stressors, can have a significant influence on the brain and body. Yet, only some individuals develop illness in response to chronic stress, such as anxiety, depression, and post-traumatic stress disorder (PTSD). Why do …

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Study Aims to Reveal Novel Drivers of Allergic Disease


Chronic allergic disorders affect millions of individuals worldwide, and their frequency is increasing, especially in children and adults living in the U.S. Often, multiple allergic diseases, such as asthma, food allergies, atopic dermatitis, and some gastrointestinal disorders can occur in a single patient. Investigators at …

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Investigation Focuses on Steroids as Sleep Apnea Treatment


Removing a child’s tonsils and adenoids, or adenotonsillectomy, currently is the primary therapy for childhood obstructive sleep apnea syndrome (OSAS), but many parents remain wary about surgery and would welcome an alternative approach. Researchers from the Sleep Center at The Children’s Hospital of Philadelphia are …

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Young Researchers Receive CPCE Awards


Medical research is a rewarding field to work in, but young investigators can find that while they have an abundance of bright ideas, funding is not as plentiful. Therefore, researchers appreciate any opportunity to get a research project off the ground, such as that offered by …

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Event Celebrates CIRP Student Research


A recent event at the Center for Injury Research and Prevention (CIRP) celebrated the wide-ranging accomplishments of a number of students who worked with CIRP staff and investigators this summer. Held August 5, the ninth Annual Student Research Day featured presentations that highlighted the scope …

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