December 2015 – Year in Review

This special issue of Bench to Bedside highlights the extraordinary research achievements at The Children's Hospital of Philadelphia in 2015. Take a glance back at the innovations, new launches, and discoveries that are improving the lives of countless children every day throughout the world.

Research Making Impacts Far Beyond the Lab


Most research progresses through incremental advances, but virtually all pediatric researchers want their work to make a big impact. Many of the research advances celebrated at The Children’s Hospital of Philadelphia in 2015 did just that, influencing multiple fields of practice, policy, or society. Cancer …

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Bold, New Initiatives Set in Motion Research Transformation


The year began at an amazing pace, with the announcement in January of a $50 million gift from Philadelphia philanthropist Raymond G. Perelman that provides direct support for a wide range of pediatric research and establishes The Children’s Hospital of Philadelphia as a global center …

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Science is a Team Sport: CHOP Research Collaborations in 2015


The spirit of collaboration shapes the research enterprise at The Children’s Hospital of Philadelphia, and a look back at stories from 2015 is full of examples. “NIH is funding a lot of multi-PI grants now, two people working on different aspects of the same thing,” …

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Unraveling Genetic Complexities Helps Separate Out Potential Therapies


Genetic discovery is far from ordinary, yet physician scientists at The Children’s Hospital of Philadelphia have become so adept at using sophisticated genomic sequencing technology that pinpointing new genes with connections to pediatric illnesses may have seemed like an everyday occurrence in 2015. Here are …

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Precision Medicine Takes Center Stage


When precision medicine took center stage in 2015, research at The Children’s Hospital of Philadelphia had a starring role. The curtain opened in January with President Obama’s launch of the Precision Medicine Initiative (PMI), which seeks to spur advances in targeted treatments for disease by …

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Research Keeping Children Safe in Hospitals and Communities


Safety is a core value at The Children’s Hospital of Philadelphia, so it should come as no surprise that detecting and addressing safety risks is a major area where CHOP researchers advanced knowledge this year. Their work spans safety in inpatient and outpatient settings and …

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Research Reaches Wide Range of Healthy Policy Issues


A common misconception is that researchers exist in an isolated world of beakers and test tubes, yet scientists’ scope of influence can extend far past their laboratories’ walls — even beyond the bedside — and into social beliefs and actions. In 2015, several researchers from …

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Technology Takes Research in New Directions


An exhilarating aspect of being a researcher at The Children’s Hospital of Philadelphia is having the opportunity to take the driver’s seat and propel medical technology forward. In 2015, investigators embarked on fascinating trips of discovery. Researchers at CHOP Center for Injury Research and Prevention (CIRP) …

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