June/July 2016

Mobile health (mHealth) technologies have the potential to speed up science and find new ways to engage youth in real time to support and encourage healthy behaviors. “You’re actually carrying on an intervention every day at every moment,” said Nadia Dowshen, MD, about mHealth research. This issue of Bench to Bedside covers four examples of the imaginative ways that our researchers are setting a new pace by integrating mHealth and social media strategies into the HIV care continuum, type 1 diabetes care, infants’ and toddlers’ sleep, and cancer survivors’ transition into adulthood.

Three Ways to Connect With Youth to Improve HIV Testing and Care


Too often, when Nadia Dowshen, MD, is in a patient exam room explaining to a teen living with HIV how antiretroviral therapy can keep the virus from destroying his immune system, he is looking at his cell phone and not fully paying attention. Could a …

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Wake Up to This Novel Data Collection Tool for Pediatric Sleep Research


One of the rites of passage into parenthood are those first few bleary-eyed months when soothing an infant to sleep seems like an impossible dream. All the lullabies, rocking, feeding, swaddling — hour after hour, night after night — can be exhausting. Many parents find …

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Ready to Be a Healthy Adult Survivor of Childhood Cancer? Text Y/N


The needle sticks, body scans, chemo infusions, radiation, and looming fears are all behind you. The ordeal of childhood cancer has ended, and you are a survivor. Now what? Time to grow up healthy. But that process is more complicated for survivors than for most …

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What’s in it for Me? Behavioral Economics to Improve Teens’ Glycemic Control


When young patients with type 1 diabetes reach adolescence and young adulthood, they tend to “fall off the cliff” and don’t take their medications or visit their healthcare providers on a consistent basis. This can send their glycemic control into a spiral leading toward short- …

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Microbiome Study of Inflammatory Bowel Disease Will Give the Gut a Holiday


Lindsey Albenberg, DO, wants to give her patients’ guts a vacation. Dr. Albenberg, a pediatric gastroenterologist at The Children’s Hospital of Philadelphia, is launching a new study of Crohn’s disease that gives the digestive tract a “holiday” by temporarily wiping out the bacteria and fungi …

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‘Y’ Could Help Answer ‘How’ for Autism Spectrum Disorder in the Brain


The Y chromosome could help point the way to new answers about the neural mechanisms of autism spectrum disorder (ASD). Studies underway at The Children’s Hospital of Philadelphia are seeking possible structural and functional differences in the brain associated with having an extra copy of …

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Study Aims to Match Injured Children to Hospitals Best Equipped for Their Care


The first responder has a critical decision to make as she loads a severely injured child into an ambulance. Take the child to the nearest hospital emergency department (ED) to be seen and stabilized as soon as possible, or go another three miles farther to …

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Time to Strengthen Parent-Pediatrician Conversations About Autism Care


“The times I have asked about treatment, I am kind of met with a blank stare,” one parent reported of the experience of discussing therapy for their child’s autism spectrum disorder (ASD) with the pediatrician. This parent’s experience is likely not unique, according to a …

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Scientists Reveal New Mechanism Adenovirus Uses to Sabotage Immune System


Adenovirus, a common human virus that usually affects the lungs and causes respiratory tract infections, is an old friend to virologists. They have long studied how this virus interacts with host cells to understand cellular processes and reveal key regulators of cellular functions. But even …

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