A team led by The Children’s Hospital of Philadelphia’s Marni J. Falk, M.D., has expanded next-generation gene sequencing tools designed to unlock the secrets hidden in nuclear DNA to analyze a separate source of DNA — that found within mitochondria.
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene mutations — mutations that would suggest new targets for neuroblastoma treatment.
The Children’s Hospital of Philadelphia has been named the nation’s best pediatric hospital by Parents magazine. In addition to the overall ranking, CHOP was ranked in the top 3 in all 6 specialties included in the survey. Parents ranked Children’s Hospital’s Cancer Center and emergency medicine first
A new study verifies the long-controversial belief that a few children, in exceptional cases, can “recover” from autism. The study, which included investigators from the Center for Autism Research, is the first solid science to confirm that, however rarely, with the help of behavioral therapy some children can make such great improvements that they no longer qualify as having autism.
Frank Balis, M.D., and John M. Maris, M.D., recently announced the appointment of Lamia P. Barakat, Ph.D., to head the Section on Behavioral Oncology. Dr. Barakat is currently the Director of Psychosocial Services for the Division of Oncology, and she will be promoted to the rank of Professor of Clinical Psychology in the Department of Pediatrics effective July 1st 2013.
By broadly comparing the DNA of children to that of elderly people, gene researchers at The Children’s Hospital of Philadelphia have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease.
It’s been nearly a decade since scientists completed the Human Genome Project — a scientific marvel that, in its essence, provided the blueprint for the genetic make-up of humans.
The Children’s Hospital of Philadelphia researchers contributed to two recent studies showing that extending cardiopulmonary resuscitation (CPR) longer than previously thought useful saves lives in both children and adults. The research teams analyzed the impact of duration of CPR in patients who suffered cardiac arrest while hospitalized.
Clinical Research Coordinators (CRCs) are an essential component of the clinical research enterprise at CHOP, serving a pivotal role in human subjects protection and overall study management. The CHOP Research Institute (CRI) is committed to providing the proper education, training, and support for the CRCs.
Our monthly online news magazine Bench to Bedside explores the fascinating research developments, discoveries, and achievements by our remarkable scientists and physicians. In each issue, see how their endeavors have a powerful impact on children's well-being.
